For many women, changes in sexual health, pleasure, or comfort can be difficult to talk about — yet they’re incredibly common. Factors like childbirth, hormonal changes, menopause, or simply aging can affect sensitivity, lubrication, and overall confidence in the bedroom.
The O-Shot® (short for “Orgasm Shot”) is a breakthrough, non-surgical treatment that’s designed to help with exactly that. It uses your own body’s natural healing power to rejuvenate vaginal and clitoral tissues, enhance sensitivity, and even support urinary control — all with minimal downtime.
If you’ve been curious about what the O-Shot is, how it works, and whether it might be right for you, this guide covers everything you need to know — from science and benefits to what to expect before and after treatment.
What Is the O-Shot®?
The O-Shot® or Orgasm Shot is a platelet-rich plasma (PRP) treatment developed by Dr. Charles Runels. It involves taking a small sample of your own blood, processing it to extract the PRP (the part rich in growth factors), and then injecting it into specific areas of the vagina and clitoris.
The O-Shot can also be performed using exosomes, which are cellular messaging signals that induce reparation, reduce inflammation, and promote regeneration.
PRP has been widely used in medicine for decades — especially in orthopedics, dermatology, and cosmetic treatments — to stimulate tissue healing, new collagen growth, and improved blood flow. The O-Shot applies that same regenerative principle to women’s sexual wellness.
Because the treatment uses your own plasma, it’s completely natural — there are no artificial chemicals or hormones involved.
How Does the O-Shot Work?
Here’s a simple breakdown of how the O-Shot® works:
Blood Draw
A small amount of blood is taken from your arm — similar to what’s done during a routine lab test.
PRP Preparation
The blood is spun in a centrifuge, which separates the platelet-rich plasma from red and white blood cells. The PRP contains high concentrations of growth factors that help regenerate tissue.
Numbing & Injection
The treatment area is numbed with a local anesthetic. Then, using a fine needle, the PRP is carefully injected into specific areas around the vaginal wall and clitoris, depending on your needs and goals.
Regeneration Phase
Over the next few weeks, the growth factors stimulate new collagen formation, tissue repair, and increased blood flow, which can lead to improved sensitivity, lubrication, and overall sexual function.
Who Can Benefit from the O-Shot®?
The O-Shot® isn’t just for women who want to enhance sexual pleasure — it’s also beneficial for those dealing with certain medical or post-hormonal issues.
You may be a good candidate if you experience:
- Low libido or decreased sexual desire
- Difficulty reaching orgasm or reduced sensitivity
- Pain or discomfort during intercourse
- Vaginal dryness (often linked to menopause)
- Mild urinary incontinence (leaking when laughing, sneezing, or exercising)
- Loss of firmness or tone in vaginal tissue
- Changes in confidence or intimacy after childbirth
Because it’s non-hormonal and uses your own blood, the O-Shot is safe for most women, including those who can’t take estrogen or who prefer natural options.
Why Choose Curativ for the O-Shot®
At Curativ, we take a holistic, science-based approach to women’s wellness.
Our medical team is trained in regenerative therapies like the O-Shot®, combining clinical expertise with compassionate care to help you feel confident, healthy, and supported every step of the way.
We don’t believe in one-size-fits-all treatments.
Your O-Shot® plan is tailored to your unique needs — addressing hormone balance, nutrition, and overall well-being to deliver lasting results that go beyond physical changes and help restore balance, vitality, and confidence from the inside out. Book your consultation today!
Benefits of the O-Shot® for Women
Every woman’s experience is unique, but the O-Shot® is known to provide a wide range of benefits that can go beyond sexual function.
Physical and Sexual Health Benefits
- Increased clitoral and vaginal sensitivity
- Enhanced ability to achieve orgasm (sometimes even multiple orgasms)
- Improved vaginal lubrication
- Reduced pain during sex
- Tighter, firmer vaginal tissue due to new collagen production
- Greater comfort and satisfaction during intimacy
Functional and Health-Related Benefits
- Reduction in urinary leakage or urgency (stress incontinence)
- Healthier vaginal tissue and better circulation
- Faster recovery after childbirth or menopause
- Relief from dryness or irritation without the use of hormones
Emotional and Quality of Life Benefits
- Boosted confidence and body awareness
- Improved connection and intimacy with partners
- Better overall sexual wellness and self-esteem
Most women report gradual improvement starting within a few weeks, with optimal results appearing around 3 months after the treatment.
How to Prepare for the O-Shot®
Preparation is simple, but following a few basic steps can help you get the best results:
- Stay well-hydrated in the days leading up to your appointment.
- Avoid blood-thinning medications or supplements (like aspirin or fish oil) for a few days, unless prescribed by your doctor.
- Eat a light meal before your treatment to avoid dizziness.
- Discuss any medications, hormone therapy, or health conditions with your provider.
After your appointment, you can return to normal activities right away, though you may want to wait about 24 hours before sexual activity.
O-Shot Risks or Complications
Because the O-Shot® uses your own blood, it’s considered one of the safest treatments available for female sexual wellness.
However, as with any medical procedure, some mild and temporary side effects can occur.
Possible Short-Term Effects
- Mild swelling or redness at the injection site
- Temporary spotting or tenderness
- Sensitivity or tingling for 24–48 hours
- Minor bruising (rare)
These typically resolve within a few days.
Rare Complications
Serious side effects are extremely uncommon, but in rare cases, patients could experience:
- Local infection (if post-care instructions aren’t followed)
- Allergic reaction to topical numbing cream
- Discomfort lasting longer than a few days
At Curativ, all O-Shot® procedures are performed by trained, certified professionals in a sterile, medical-grade environment to ensure maximum safety and comfort.
What to Expect During the O-Shot Procedure
If you’re nervous about the idea of injections — don’t worry. The procedure is surprisingly simple and designed for comfort.
Here’s what typically happens during an O-Shot® appointment:
- Consultation: Your provider will review your medical history, symptoms, and goals to make sure the O-Shot is a good fit for you.
- Preparation: Blood is drawn from your arm, then processed to isolate the PRP.
- Numbing: A topical numbing cream is applied to minimize any discomfort. Most women say they feel pressure, not pain.
- Injection: The PRP is injected into precise areas around the vaginal wall and clitoris. The process only takes a few minutes.
- Recovery: You can go home right after. There’s no downtime — you can return to normal activities, including sexual activity, usually within 24 hours.
The entire visit typically takes less than an hour.
How Long Does the O-Shot Last?
Results vary by person, but most women begin noticing improvements within 2–4 weeks, with continued enhancement for up to 3 months as new tissue regenerates.
The effects usually last 12 to 18 months, depending on your body, hormones, and lifestyle. Many women choose to schedule maintenance treatments once a year to maintain results.
The Bottom Line
The O-Shot® represents an exciting advancement in women’s health — one that prioritizes comfort, confidence, and natural rejuvenation.
It’s more than a treatment for sexual enhancement; it’s a way to reconnect with your body and feel good again, inside and out.
If you’ve been looking for a safe, effective, and natural approach to improving intimacy and wellness, the O-Shot® might be worth exploring — with the guidance of a trusted, experienced provider like us.